Πλοήγηση ανά Συγγραφέα "Braliou, G. G."
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2-Oxoglutarate-dependent oxygenases control hepcidin gene expression
Braliou, G. G.; Falzacappa, M. V. V.; Chachami, G.; Casanovas, G.; Muckenthaler, M. U.; Simos, G. (2008)Background/Aims: Hepcidin is a liver-produced hormone that regulates systemic iron homeostasis. Hepcidin expression is stimulated upon iron overload or inflammation while iron deficiency, anemia and tissue hypoxia are ... -
Polymorphisms of the CD24 Gene Are Associated with Risk of Multiple Sclerosis: A Meta-Analysis
Braliou, G. G.; Pantavou, K. G.; Kontou, P. I.; Bagos, P. G. (2015)CD24 is a cell-surface protein mainly expressed in cells of the immune and central nervous system (CNS), cells that play a critical role in the development of multiple sclerosis (MS). In the current study, we investigated ... -
Reconstitution of human hypoxia inducible factor 1 (HIF-1) in yeast cells: a simple in vivo system to identify hif-1 inhibitors
Braliou, G. G.; Venieris, E.; Simos, G. (2005) -
Reconstitution of human hypoxia inducible factor HIF-1 in yeast: A simple in vivo system to identify and characterize HIF-1 alpha effectors
Braliou, G. G.; Venieris, E.; Kalousi, A.; Simos, G. (2006)Hypoxia inducible factor I (HIF-1), the master regulator of hypoxia-activated genes, is involved in many diseases and is a valid drug target. In order to develop a simple and genetically tractable in vivo system for HIF-1 ... -
The role of genetic polymorphisms of the Renin-Angiotensin System in renal diseases: A meta-analysis
Braliou, G. G.; Grigoriadou, A. M. G.; Kontou, P. I.; Bagos, P. G. (2014)Renal failure has a complex phenotype resulting from an underlying kidney disease as well as environmental and genetic factors. In the present study we performed a systematic review and meta-analyses to evaluate the ... -
Transport of hypoxia-inducible factor HIF-1 alpha into the nucleus involves importins 4 and 7
Chachami, G.; Paraskeva, E.; Mingot, J. M.; Braliou, G. G.; Gorlich, D.; Simos, G. (2009)Hypoxia-inducible transcription factor 1 (HIF-1) mediates the cellular response to hypoxia. HIF-1 activity is controlled via the synthesis, degradation or intracellular localization of its alpha subunit. HIF-1 alpha contains ...